5f-sdb-005

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It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analogue of PB-22 where the 8-hydroxyquinoline .

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Description

5-fluoro SDB-005 is an analog of SDB-005, a synthetic cannabinoid (CB) that activates the central CB1 receptor (EC50 = 21 nM) preferentially over the peripheral CB2 receptor (EC50 = 140 nM).While the properties of this compound are not known, the addition of fluorine to the terminal carbon of the alkyl chain in similar cannabimimetic compounds typically increases affinity for both CB receptors significantly. This product is intended for research and forensic applications.SDB-005 with the systematic or IUPAC name of 1-(5-Fluoro-pentyl)-1H-indazole-3-carboxylic acid naphthalen-1-yl ester is an analog of SDB-006. The molecular formula for 5F-SDB-005 is C23H21FN2O2 with a molecular weight of 376.42 and an exact mass of 376.16.

A derivative of SDB-005 that has a fluorine atom at the terminal carbon of the pentyl chain
5-fluoro SDB-005 is an analog of SDB-005, a synthetic cannabinoid (CB) that activates the central CB1 receptor (EC50 = 21 nM) preferentially over the peripheral CB2 receptor (EC50 = 140 nM). While the properties of this compound are not known, the addition of fluorine to the terminal carbon of the alkyl chain in similar cannabimimetic compounds typically increases affinity for both CB receptors significantly. This product is intended for research and forensic applications. SDB-006 is a cannabimimetic indole that binds the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with EC50 values of 19 and 134 nM, respectively. SDB-006 was discovered during research of the related compound JWH-018 adamantyl carboxamide, which has been sold illicitly in herbal blends.

 

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