4-ACO-DMT CRYSTAL

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Natural and synthetic tryptamines are used recreationally for their hallucinogenic and stimulant properties. In recent years, synthetic tryptamine analogs have experienced a resurgence of abuse. The main drivers for this resurgence include their ease of availability on clandestine and legal websites combined with a growing trend among drug users to vaporize tryptamines using e-cigarette devices

Substituted tryptamine analogs including 5-MeO-DALT, 4-OH-DiPT and 4-AcO-DMT can offer increased potencies compared to natural tryptamines as a result of functional group modification. These novel psychoactive substances (NPS) can be synthesized from naturally-occurring tryptamines, such as N,N-dimethyltryptamine (DMT) or psilocin, by introducing a methoxy, hydroxy or acetoxy group at the four or five position of the indole ring. Tryptamines with substitution at the five position typically possess more hallucinogenic potency than their unsubstituted counterparts or analogs with indole ring substitutions at the six or seven positions. 5-MeO-DiPT, for example, is seven times more potent than DMT3.

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Description

4-AcO-DMT (O-Acetylpsilocin, 4-Acetoxy-dimethyltryptamine) is a synthetic psyhedelic from the group of triptamines. It should be decomposed into psilocin (a substituted tryptamine alkaloid that is present in most psyhedelic mushrooms), but there is a high probability that 4-AcO-DMT itself is also psychoactive.

With 4-AcO-DMT specifically, a study was done in heroin and nicotine dependent ratsand mice, where it was shown that a single administration of 4-Aco-DMT to the VTA (Ventral Tegmental Area), blocked the mechanism that switches a drug-naive state to a drug-dependent one, as well as the conditioned aversive response to drug-withdrawal.

  • The use of 4-AcO-DMT is not recommended in case of mental health problems .
  • Always use a precise balance for the preparation of doses ! Dosage assessments are extremely dangerous and may indicate a difference between a pleasant experience and an overdose!
  • When using 4-AcO-DMT, we recommend a consistent observation of the general guidelines for reducing harm in the use of hallucinogens: choosing appropriate settings, place and time, having a trip-sitter, a sober person who will take care of your well-being during the hit, .. You read more  here

You can experience a very unpleasant experience, the so-called “bad trip”. The consequences can be long-term and unpleasant. In case of problems with the integration of difficult experiences under the influence of hallucinogens, you can contact our counseling service

4-AcO-DMT  is a psychedelic  tryptamine first reported in 1963 when it was patented by Albert Hofmann and Franz Troxler by Sandoz.
It is very likely that O-acetylpsilocin is metabolized in the body to psilocin, as well as psilocybin (the active ingredient of magic mushrooms)

4-AcO-DMT  is a psychedelic  tryptamine first reported in 1963  when it was patented by Albert Hofmann and Franz Troxler by Sandoz.
It is very likely that O-acetylpsilocin is metabolized in the body to psilocin, as well as psilocybin (the active ingredient of magic mushrooms, eg Psilocybe cubensis).
However, some consumers report significant differences in the outcome (or differences in duration of experience) compared to psilocybin, either because of subjective expectations or because 4-AcO-DMT itself is also psychoactive and in addition to psilocin is metabolized.

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